A comparison of the cognitive deficits seen in myalgic encephalomyelitis to Alzheimer's Disease. Scholey, A et al. Proceedings of the British Psychological Society, 1999, January, 12. Another symptom which is characteristic of ME is impaired cognitive functioning (e.g. poor memory etc.). Early reports revealed major deficits, but these were forgotten when the research found only subtle changes in CFS. The following study is noteworthy because it focused exclusively on people with ME (London criteria). Tests were done on 20 patients and it was found that their performance was significantly inferior to that of healthy controls. Moreover, when the results were compared to those from 782 patients with Alzheimer's Disease (AD), the ME group fell between mild and moderate Alzheimer's patients on most tasks. "The extent as well as the range of the impairments ... confirms the severe nature of ME." These findings deserve to be taken seriously because they were reported by one of Britain's leading experts in the field. The results not only support anecdotal reports from patients but they underline once again that generalisations about CFS may not apply to the various subgroups.